Another major breakthrough was reported in the search for a cure for AIDS.
After bone marrow transplantation, two HIV-infected men have no longer any trace of the virus that causes AIDS in their cells, researchers report.
Lymphocytes are a type of white blood cells and are a key part of the immune system.
U.S. investigators suspect that the bone marrow transplant, together
with the continuation of antiretroviral therapy as a result of the
dramatic effects evident eight months after transplantation. They are
scheduled to present preliminary findings Thursday at the International
AIDS Conference in Washington, DC.
HIV patients receiving antiretroviral therapy often get “an
undetectable viral load” meaning no virus particles in their blood. But
they still have latent HIV in their cells, and if antiretroviral therapy
was stopped, it could reactivate latent HIV.
Because they had no traces of HIV in their white blood cells is an
indication that the “pool” of latent HIV may have been eliminated, the
researchers believe.
At this point, researchers are far from saying these patients are
cured. However, the findings are “exciting,” said Dr. Savita Pahwa,
director of the Center for AIDS Research at the University of Miami
Miller School of Medicine, who was not involved in the study.
“Each clue that is obtained that it is possible to eliminate latent HIV must be investigated,” she said.
“The elimination of the reserve HIV is the key to a cure,” said
Pahwa. She stressed it would only be possible to say that these patients
were “functionally cured” if the virus will not reactivate when the
patients were off antiretroviral therapy.
No comments:
Post a Comment